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Name
ID

Brca2
breast cancer 2, early onset
MGI:109337

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Leukopenia	T-cell acute lymphoblastic leukemias	Acute myeloid leukemia	Lymphadenopathy	Hepatosplenomegaly	Peritoneal abscess	Inflammatory abnormality of the eye	Recurrent urinary tract infections
Disease(s) Associated with BRCA2	Leukopenia	T-cell acute lymphoblastic leukemias	Acute myeloid leukemia	Lymphadenopathy	Hepatosplenomegaly	Peritoneal abscess	Inflammatory abnormality of the eye	Recurrent urinary tract infections
Fanconi anemia
Fanconi anemia complementation group D1
pancreatic cancer
uveal melanoma

Mouse Phenotypes		immune system phenotype	increased T cell apoptosis	increased thymus weight	spleen hypoplasia	sepsis
Availability	Mouse Genotype	immune system phenotype	increased T cell apoptosis	increased thymus weight	spleen hypoplasia	sepsis
	Brca2^tm1Cam/Brca2^tm1Cam
	Brca2^tm1Hst/Brca2^tm1Hst
	Brca2^tm1Kamc/Brca2^tm1Kamc
	Brca2^tm1Mak/Brca2^tm2Mak Tg(Lck-cre)548Jxm/0 (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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